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DNA Fingerprinting/DNA Profiling Activity: Learn & Model - NO PREP!

Rated 4.63 out of 5, based on 30 reviews
4.6 (30 ratings)
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Science of Curiosity
2k Followers
Grade Levels
9th - 12th, Homeschool
Resource Type
Standards
Formats Included
  • Google Drive™ folder
$3.00
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Science of Curiosity
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What educators are saying

I used this with my AP students to review Gel Electrophoresis and they really enjoyed it and were able to refer back to it during our unit test! Thank you so much!
My students really enjoyed the challenge of this activity. The readings were challenging for most of my students but I was able to scaffold the reading with the help of my co teacher. I look forward to using more from this teacher.
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Description

Model DNA Fingerprinting/DNA Profiling with this digital resource! Your students will walk through the Three Steps of making a DNA Fingerprint. Then they use what they learned to create four DNA Fingerprints and solve a murder case!

All learning and instructions for the activity are included on the slides for them - truly no prep! Students can complete the activity on their own - or work in pairs.

Resource includes:

  • How are DNA Fingerprints Made? Fourteen interactive Google Slides that teach students the process, tools needed, and reason behind each step of DNA Fingerprinting. Students model the process of DNA Fingerprinting as they learn. (See details below)
  • DNA Fingerprinting Notes: This graphic organizer provides students a place to record the steps of DNA Fingerprinting. It can be printed and completed on paper, or digitally on Google Slides
  • DNA Fingerprinting Review: A self grading Google Form with 12 multiple choice questions, a perfect informal assessment to see what your students have learned.
  • Complete Answer Key 
  • Teacher Guide for how to use the activity

All parts of this resource are editable!

Details - What your students will learn:

  • First, students are introduced to the crime - the murder of Harry Monroe. Who did it? Blood spatter evidence suggests that the attacker was also injured. A blood sample is taken to make a DNA Fingerprint from.
  • Students meet the three suspects, their possible motives and stated alibis. DNA samples are taken from them to compare with the blood at the crime scene.
  • Three steps of DNA Fingerprinting:
    • Cut the DNA with a Restriction Enzyme - students drag and drop ‘scissors’ that represent the restriction enzyme to cut samples of DNA into different sized pieces
    • Copy the DNA Pieces with the PCR Machine - students make copies of each piece of DNA, and learn why this step is so important
    • Separate DNA Pieces by Size with a Gel Electrophoresis Machine - Simple illustrations ‘zoom in’ on DNA in the gel, explain why the DNA moves through the gel, and why smaller pieces move quickly to the bottom while larger pieces get stuck near the top. 
  • Finally, students drag fragments of DNA through a ‘gel’, making four DNA Fingerprints (that of the crime scene blood and of the three suspects). The DNA FIngerprint of only one suspect matches the blood! 
  • Along the way students answer questions about what they learn by typing directly onto the Google Slides

I love seeing my students light up when they solve the case!

Looking for more Forensic DNA Evidence resources? Here is the full Unit! 

Here are some other fun Forensic Science lessons and activities!

**Stay Curious!**

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Standards

to see state-specific standards (only available in the US).
NGSSHS-LS1-1
Construct an explanation based on evidence for how the structure of DNA determines the structure of proteins, which carry out the essential functions of life through systems of specialized cells. Assessment does not include identification of specific cell or tissue types, whole body systems, specific protein structures and functions, or the biochemistry of protein synthesis.

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